SKU: 3162844118

Kupfertoxikose (CT) - Labrador Retriever

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Description

Kupfertoxikose (CT) - Labrador RetrieverStoffwechselstrungen des Kupfers sind genetische Strungen des Kupferstoffwechsels in der Leber, die durch Mutationen in zwei Genen verursacht werden, die Kupfertransporter kodieren ATP7A und ATP7B. Der ATP7A Transporter ist entscheidend fr den Kupfertransport von Fibroblasten in die Leber und der ATP7B ist entscheidend fr den Kupferexport aus der Leber. Mutationen im ATP7A fhren zu einem defekten ATP7A Transporter, sodass das Kupfer nicht richtig aus

Stoffwechselstörungen des Kupfers sind genetische Störungen des Kupferstoffwechsels in der Leber, die durch Mutationen in zwei Genen verursacht werden, die Kupfertransporter kodieren – ATP7A und ATP7B. Der ATP7A-Transporter ist entscheidend für den Kupfertransport von Fibroblasten in die Leber und der ATP7B ist entscheidend für den Kupferexport aus der Leber. Mutationen im ATP7A führen zu einem defekten ATP7A-Transporter, sodass das Kupfer nicht richtig aus den Fibroblasten exportiert und in die Leber importiert werden kann, was zu einem Kupfermangel in der Leber führt. Dies führt zu Menkes-Krankheit, einer tödlichen neurodegenerativen Erkrankung, die durch zerebrale und zerebelläre Degeneration, Gedeihstörung, grobes Haar und Bindegewebsanomalien gekennzeichnet ist. Währenddessen führen die Mutationen im ATP7B-Gen zu einem defekten ATP7B-Transporter, sodass das Kupfer nicht richtig aus der Leber exportiert werden kann, was zu einer Kupferansammlung in der Leber und sekundär im Gehirn führt. Dies führt zu Morbus Wilson, was bei mittelalten Hunden zu Zirrhose und neuronaler Degeneration führt. Die Mutation im ATP7A-Gen hat eine X-chromosomale Vererbung und die Mutation im ATP7B-Gen hat eine unvollständig dominante Vererbung. Störungen treten bei Labrador Retrievern und Dobermann Pinschern auf. Bei Dobermann Pinschern werden jedoch Mutationen in beiden Genen gefunden, aber nur die Mutation im ATP7B kann zu einer Störung führen, in diesem Fall Morbus Wilson. Bei Labrador Retrievern können Mutationen nur in einem oder in beiden Genen gleichzeitig vorhanden sein. Mutationen in beiden Genen gleichzeitig können zu einer abnorm hohen Kupferansammlung führen, die zu Kupfertoxikose führt, insbesondere bei Hündinnen.

Vererbung: komplex

Mutation: ATP7A und ATP7B Gen

Gentest: Die Methode, die für den Gentest verwendet wird, ist äußerst genau und ermöglicht eine vollständige Unterscheidung zwischen betroffenen Tieren, Trägern und gesunden Hunden. DNA-Tests können in jedem Alter durchgeführt werden.

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SKU: 3162844118

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4.4 ★★★★★
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Fulano y Fulanita
Pawtucket, US
★★★★★ 4
Slight odor, more flexible than I expected
Color: Gold, Color: Gold
These looked like they were going to be heavy duty, but they were more flexible than I expected (see video clip). They probably still will work well, but if you’re poking your fork into something stiff, expect that the fork might bend some. There was a slight chemical odor when I opened the package, and I’m not a fan of that. As someone with MCS, I have to avoid exposure to fragrances and other harmful chemicals, and it makes me wonder what these are coated with. The gold might be cute for the aesthetic you’re going for with a particular gathering or party, but I find it unnecessary. I would rather go with the real heavy duty ones that are clear plastic from a club warehouse rather than these gold ones. I feel that these are overpriced for the quality, but not a bad price if all you’re going for is the gold aesthetic.
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Reviewed in the United States on March 6, 2026
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Sara D
Lowell, US
★★★★★ 5
Nice, high end look, disposable
Color: Gold, Color: Gold
I hate to spend a lot of money on something that's just going to be thrown away, so typically buy dollar store disposable silverware for parties and gatherings. But every once in a while, you want something more upscale or high end looking. Enter this pricy but pretty plastic silverware. It is perfect for a wedding, anniversary, shower or other event where you want a nicer look instead of basic. It is sturdy. You won't have to worry about it breaking as someone spears a bite of chicken. It looks great! There's only so much you can do with plastic ware but for what it is, it looks really nice.
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Reviewed in the United States on March 24, 2026
D
Verified Purchase
Drew Setzer
Birmingham, US
★★★★★ 5
Great value and great biodegradable plates for snacks or lods
Size: 6", Size: 6"
These plates were exactly what I was looking for! These 6" plates are smaller ones, so if you need larger ones, then get the 8" ones:)
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Reviewed in the United States on May 17, 2026
K
Verified Purchase
K Harris
Draper, US
★★★★★ 5
Great value for very sturdy, leak free plates
Size: 6"
Really like these plates! They had the best price per plate & come in a large quantity which is a huge plus for me. We use them to feed our cats wet food & sometimes water & the liquids have never leaked through the plates They are the perfect size for feeding, 1 plate will easily hold a can of cat food. They are very sturdy & don't slide across the floor while the cats are eating off them.
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Reviewed in the United States on May 3, 2025
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The wife
Battle Creek, US
★★★★★ 5
Good quality
Size: 6"
Good quality
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Reviewed in the United States on October 21, 2025

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