SKU: 3162844118

Kupfertoxikose (CT) - Labrador Retriever

Sale price$44.10 Regular price$49.00
Save 10%

Pay in installments of $12.25 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 13 - Aug 18

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Kupfertoxikose (CT) - Labrador RetrieverStoffwechselstrungen des Kupfers sind genetische Strungen des Kupferstoffwechsels in der Leber, die durch Mutationen in zwei Genen verursacht werden, die Kupfertransporter kodieren ATP7A und ATP7B. Der ATP7A Transporter ist entscheidend fr den Kupfertransport von Fibroblasten in die Leber und der ATP7B ist entscheidend fr den Kupferexport aus der Leber. Mutationen im ATP7A fhren zu einem defekten ATP7A Transporter, sodass das Kupfer nicht richtig aus

Stoffwechselstörungen des Kupfers sind genetische Störungen des Kupferstoffwechsels in der Leber, die durch Mutationen in zwei Genen verursacht werden, die Kupfertransporter kodieren – ATP7A und ATP7B. Der ATP7A-Transporter ist entscheidend für den Kupfertransport von Fibroblasten in die Leber und der ATP7B ist entscheidend für den Kupferexport aus der Leber. Mutationen im ATP7A führen zu einem defekten ATP7A-Transporter, sodass das Kupfer nicht richtig aus den Fibroblasten exportiert und in die Leber importiert werden kann, was zu einem Kupfermangel in der Leber führt. Dies führt zu Menkes-Krankheit, einer tödlichen neurodegenerativen Erkrankung, die durch zerebrale und zerebelläre Degeneration, Gedeihstörung, grobes Haar und Bindegewebsanomalien gekennzeichnet ist. Währenddessen führen die Mutationen im ATP7B-Gen zu einem defekten ATP7B-Transporter, sodass das Kupfer nicht richtig aus der Leber exportiert werden kann, was zu einer Kupferansammlung in der Leber und sekundär im Gehirn führt. Dies führt zu Morbus Wilson, was bei mittelalten Hunden zu Zirrhose und neuronaler Degeneration führt. Die Mutation im ATP7A-Gen hat eine X-chromosomale Vererbung und die Mutation im ATP7B-Gen hat eine unvollständig dominante Vererbung. Störungen treten bei Labrador Retrievern und Dobermann Pinschern auf. Bei Dobermann Pinschern werden jedoch Mutationen in beiden Genen gefunden, aber nur die Mutation im ATP7B kann zu einer Störung führen, in diesem Fall Morbus Wilson. Bei Labrador Retrievern können Mutationen nur in einem oder in beiden Genen gleichzeitig vorhanden sein. Mutationen in beiden Genen gleichzeitig können zu einer abnorm hohen Kupferansammlung führen, die zu Kupfertoxikose führt, insbesondere bei Hündinnen.

Vererbung: komplex

Mutation: ATP7A und ATP7B Gen

Gentest: Die Methode, die für den Gentest verwendet wird, ist äußerst genau und ermöglicht eine vollständige Unterscheidung zwischen betroffenen Tieren, Trägern und gesunden Hunden. DNA-Tests können in jedem Alter durchgeführt werden.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 3162844118

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.6 ★★★★★
Based on 17 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
B
Verified Purchase
BOGDAN
Omaha, US
★★★★★ 5
Excellent
I will buy again this products!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 12, 2025
E
Verified Purchase
Elizabeth
Belleville, US
★★★★★ 4
They are literally not heavy
They are narrow for my face
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2025
S
Sam Beckett
Massapequa, US
★★★★★ 5
Tropical Fringe Fun for My Summer Outfits
Color: Natural, Color: Natural
I am absolutely obsessed with this straw purse because it feels like a vacation in my hand. The first thing I noticed is how the raffia fringe has this playful half moon shape that looks like a little lion mane but in a very high fashion way. My daughter even joked that it looks like a giant fancy taco which makes it such a fun and unique piece to carry around. It is incredibly lightweight which is a huge relief because I do not want to carry a heavy bag when the weather is hot. Even though it looks compact on my mannequin, it is surprisingly roomy inside and fits my phone and all my daily essentials without feeling stuffed. The magnetic closure is quite strong so I do not have to worry about my things falling out while I am walking around a summer party or a night out. The neutral tan and cream colors in the fringe make it very easy to match with almost any outfit I own. I really appreciate the small metal brand patch on the front because it gives the bag a more polished and expensive look than a typical straw tote you might find at a souvenir shop. One thing to keep in mind is that the raffia is very textured so you should probably be careful with delicate silk fabrics so it does not snag. It feels very sturdy and well made for something that is woven from grass and I love how the fringe adds so much movement when I am moving around. This bag is definitely going to be my go to accessory for the rest of the season because it is both stylish and very practical for my needs.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 2, 2026
Q
Queen Of Nightlife
Dallas, US
★★★★★ 5
👜 Effortless Spring-to-Summer Clutch That Feels One-of-a-Kind
Color: Natural
👜 Effortless Spring-to-Summer Clutch That Feels One-of-a-Kind I’ve been a longtime fan of Sam Edelman, especially because they actually make stylish pieces that work for real life. So when I saw this clutch, I had a feeling it would be good… but I didn’t expect it to hit *this* level. This bag is a vibe. The raffia texture and that half-moon fringe give it such a unique, standout look without trying too hard. It feels like the perfect piece to roll right into spring and carry straight through summer. Think beach days, dinners out, travel nights, all of it. What I love most is that it doesn’t look like everything else out there. It feels original, like you found something special instead of just grabbing another basic clutch. It’s lightweight, easy to carry, and the magnetic closure keeps things simple and secure. It also pairs effortlessly with different outfits. You can dress it up or keep it casual and it still works. Now let’s be real, it’s a designer piece, so it’s not cheap. But for the style, quality, and uniqueness, I do think it delivers strong value for money. Five stars from me. This one’s coming with me everywhere this season ☀️
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 12, 2026
H
Hidd
Louisville, US
★★★★★ 5
Super cute clutch!
Color: Natural
This is a beautiful clutch. I got the “Natural” color, and the tones are definitely subtle. I am already eyeing the Spicy one too, but for me, the natural color is just easier to match with outfits. I did laugh though because my nephew said it looks like a taco, but honestly that just makes me love it even more! The material is extremely nice, it feels very premium and well made. I was a bit nervous because I have had cheaper bags with that shredded-style material that flakes and falls apart, but that is not the case here. It feels really well made. I cannot speak for long-term durability yet, but so far there is no shedding or anything like that. I also did not notice any loose stitching or threads at all, it just feels like a high-quality bag. It has small magnets to keep it closed, which work nicely. There is not a ton of space since it is a clutch, but there is still enough room for my phone and a few small items, so it works well. Overall, it is just a really gorgeous, well made bag, and I really do not have anything to complain about.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 2, 2026

recommand products