SKU: 6591556221

Natural Factors Acetyl-L-Carnitine 500mg - 60 Capsules

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Description

Natural Factors Acetyl-L-Carnitine 500mg - 60 CapsulesProduct Information Carnitine and its derivatives exist in a carnitine pool in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl L carnitine (ALC) is the most important derivative of carnitine and

Product Information

Carnitine and its derivatives exist in a carnitine “pool” in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl-L-carnitine (ALC) is the most important derivative of carnitine and occurs naturally in the body. Because ALC is considered to have greater bioavailability and is therefore more able to cross neurological membranes, it is the preferred form to take for promoting neurological health. 

The levels of carnitine and its derivatives are critical to normal biological functioning. Carnitine is present in the diet in red meats and dairy products, and humans can make carnitine from the amino acids lysine and methionine. However, carnitine deficiency can occur with metabolic disorders, and in conditions such as diabetic neuropathy (nerve pain) and other complications of diabetes. 

ALC has been studied in various conditions including neurological and cognitive disorders such as Alzheimer’s, dementia, depression, neuropathies, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica.

Main selling features

  • The most important derivative of carnitine, and the preferred form to take, as it is the most bioavailable
  • Able to cross the blood-brain barrier
  • Has many neurological benefits, including cognitive ability, memory, and mood
  • Naturally occurring nutrient, free from toxic effects

How it works

Acetyl-L-carnitine is the most abundant naturally occurring derivative of carnitine. ALC helps the body produce energy at the cellular level; regulates carbohydrate, lipid and protein metabolism; facilitates fatty acid entry into the mitochondria; and maintains the homeostasis of coenzyme A. ALC also displays potent antioxidant effects and supports repair mechanisms. ALC has been shown to support heart and brain function, muscle movement, and numerous other body processes. 

ALC protects and enhances the activity of neurons and transmitters in the mitochondria and reduces oxidative stress. By improving cellular function and effi ciency in the mitochondria, ALC stabilizes the fl uidity and function of cell membranes, and improves energy production. ALC is involved in peripheral nerve regeneration and has shown promise in improving neuropathy. Because ALC is able to cross the blood-brain barrier it is able to exert its neuroprotective effects in the brain. Studies have shown ALC can improve cognitive performance and mood by protecting against oxidative stress and reducing or blocking the neuronal death that occurs with dementia and other neurodegenerative conditions. 

Supplementation with ALC may be useful in a broad range of conditions, including Alzheimer’s, dementia, age-related memory loss and depression, fatigue, diabetic neuropathy, and cardiovascular disease.

Positioning Line

Boosts physical and mental energy

Ingredients
Each Capsule Contains:  
Acetyl-L-Carnitine 
(N-Acetyl L-carnitine hydrochloride)
500 mg

Non-Medicinal ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.  

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SKU: 6591556221

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4.2 ★★★★★
Based on 22 reviews
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Verified Purchase
Nunya B
San Leandro, US
★★★★★ 4
So cute
Size: Large, Color: Pumpkin
My French Bulldogs have really strong jaws and are aggressive chewers. These really are sturdy and last a good amount of time. They are a bit heavy and awkward for my dogs to hold onto but they do like them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 25, 2026
B
Verified Purchase
Brandy REVIEWS
Chelsea, US
★★★★★ 5
Cute toy and super tough!
Size: Small, Color: Lobster
My small dog is a serious chewer, and this lobster toy has been holding up great. Usually, he destroys toys within a day, but this one’s still going strong after a couple of weeks. The shape is perfect — easy for him to grab and chew, and the little claws keep him entertained. The filet mignon flavor must be good because he goes right for it every time. It’s sturdy without being too hard on his teeth, and it doesn’t leave any mess or pieces behind. If you’ve got a small but mighty chewer, this one’s definitely worth it. Cute design, lasts forever, and keeps my pup busy — total win. 🦞🐾
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 26, 2025
S
Verified Purchase
SS
Chelsea, US
★★★★★ 5
Excellent toy
Size: X-Large, Color: Lobster
Very durable. Dog who has destroyed every toy ever purchased loves this and it is still in great condition.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 21, 2026
H
Verified Purchase
Honorific Tails
Los Angeles, US
★★★★★ 3
Cheese the Day with Nylabone's Power Chew Cheese Chew Toy!
Size: X-Large, Color: Cheese
As a devoted dog parent, I've always believed that our furry friends deserve the best, especially when it comes to their favorite pastime—chewing! Nylabone's Power Chew Cheese Chew Toy is a game-changer that's added an extra layer of excitement to our dog's chewing routine. **Chew-Tastic Design:** First things first, the cheese-inspired shape of this chew toy is a hit in our household. Our dog can't resist its quirky design, and it's become a beloved addition to his chew toy collection. It's like a fun surprise every time he reaches for it! **Flavor Pockets for Fun:** What truly sets this chew toy apart is its flavor pockets. We fill them with spreadable treats, turning regular chew time into an epic adventure. Our dog absolutely loves the challenge of getting every last bit of treat, and it keeps him engaged for hours. **Dental Health Bonus:** Beyond the fun factor, the unique textures on this toy serve a dual purpose. Not only do they provide extra sensory enjoyment for our pup, but they also help clean his teeth as he chews. It's a win-win for both entertainment and dental health. **Built to Last:** Now, let's talk durability. Our dog is a power chewer, and this toy has proven to be up to the challenge. Made from Nylabone's most robust material, it's stood the test of time, promoting healthy chewing habits and saving our furniture from destruction. **Satisfaction All Around:** This chew toy isn't just for our dog's enjoyment; it brings joy to our family too. Seeing our furry friend so engaged and happy is priceless. It satisfies his natural urge to chew while teaching him healthy chewing habits. **A Flavorful Experience:** Did I mention the cheese flavor? It runs throughout the toy, adding another layer of enjoyment for our pup. It's like a delicious treat that never ends! **Perfect for Big Dogs:** As the proud parent of an extra-large dog, we opted for the "Souper" size, designed for dogs over 50 pounds. It's the perfect size for our gentle giant. In conclusion, Nylabone's Power Chew Cheese Chew Toy has become an integral part of our dog's life. It's more than just a chew toy; it's an adventure, a dental health solution, and hours of entertainment all rolled into one. We've embraced the mantra of "Cheese the Day" with this fantastic chew toy, and we wholeheartedly recommend it to fellow dog parents looking to add more joy and flair to their furry friend's life!
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Reviewed in the United States on October 27, 2023
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Verified Purchase
Danielle L Dykhouse
Natrona Heights, US
★★★★★ 5
Dog approved.
Size: X-Large, Color: Cheese
I’m a 70 lbs Goldendoodle (supposed to be 65, don’t ask) and I love cheese. Real cheese. Sharp cheddar with sourdough bread is my dream, but apparently I’m “on a health journey,” so my people bought me this instead. Does this bone actually taste like cheese? No. I am not fooled. Do I still enjoy chewing it loudly while my humans are trying to watch TV? Absolutely yes. This bone satisfies my need to chew and my emotional desire for cheese-adjacent activities. It keeps me busy, saves the furniture, and lets me crunch dramatically during important dialogue scenes. The yellow color is nice — very cheese-coded — although some cheeses are white, so just something to consider for future versions. Also, good news: it doesn’t smell like cheese at all, which my humans seem very grateful for. Apparently they don’t want the carpet to smell like a deli. Weird. Final verdict: Not cheese. Still enjoyable. Would chew again. ~Barley
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Reviewed in the United States on February 4, 2026

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