SKU: 43806211468

Biotinylated CD47 His&Avi Tag Protein, Mouse

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Description

Biotinylated CD47 His&Avi Tag Protein, MouseProduct Specification Species Mouse Synonyms MER6, IAP, OA3 Accession Q61735 1 Amino Acid Sequence Gln19 Lys140, with C terminal 8*His&Avi tag QLLFSNVNSIEFTSCNETVVIPCIVRNVEAQSTEEMFVKWKLNKSYIFIYDGNKNSTTTDQNFTSAKISVSDLINGIASLKMDKRDAMVGNYTCEVTELSREGKTVIELKNRTVSWFSPNEKGGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE Expression System HEK293 Molecular Weight 33 43kDa Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance

Product Specification


Species Mouse
Synonyms MER6, IAP, OA3
Accession Q61735-1
Amino Acid Sequence

Gln19-Lys140, with C-terminal 8*His&Avi tag QLLFSNVNSIEFTSCNETVVIPCIVRNVEAQSTEEMFVKWKLNKSYIFIYDGNKNSTTTDQNFTSAKISVSDLINGIASLKMDKRDAMVGNYTCEVTELSREGKTVIELKNRTVSWFSPNEKGGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE

Expression System HEK293
Molecular Weight 33-43kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Biotin
Tag Avi Tag, His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.

Reference

1. Brown E J. et al. (2001) Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 11(3): 130-135. 2. Oldenborg P A. (2004) Role of CD47 in erythroid cells and in autoimmunity. Leuk Lymphoma. 45(7): 1319-1327. 3. Kaczorowski D J. et al. (2007) Targeting CD47: NO limit on therapeutic potential. Circ Res. 100(5): 602-603.

Background

CD47, also known as Integrin-associated protein (IAP), is a typical representative of the "marker of self" of targets expressed by all types of cells. CD47 is a glycoprotein with an immunoglobulin variable N-terminal domain, five transmembrane domains, and a short C-terminal intracellular tail with four variably different splicing isomers, resulting in four isoforms. CD47 is an immune cell group that plays a major role in targeted tumor immunotherapy. CD47 expressed by cancer cells interacts with SIRP-α and SIRP-γ expressed by NK cells to protect cancer cells from phagocytosis and elimination. CD47 was highly expressed in a variety of solid tumor cells and malignant hematoma cells, and its expression level was positively correlated with disease progression.

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SKU: 43806211468

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Tom
Los Angeles, US
★★★★★ 5
Perfect diapers -soft,absorbent,and no leaks!
Size: Size 6, Unit Count: 48
These Pampers diapers are amazing! The material is very soft and comfortable for my baby. They have great absorbency and can last through the night without any leaks. I also noticed no rashes or irritation, which is very important to me. The fit is perfect and easy to put on. Definitely one of the best diapers I’ve used. Highly recommended!
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Reviewed in the United States on April 11, 2026
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Eleventh Street Beauty
Los Angeles, US
★★★★★ 5
Mom of 6 approved
Size: Size 3, Unit Count: 78
I'm a mom of 6 and these are the best diapers. No problems. Extremely soft and comfy. Easiest diaper to get on a toddler doing the alligator roll. I put my hands through the leg holes and grab their feet to pull them through for easiest pull on. No problems with blow outs. I love the new tear off feature, so no issue with getting them off. I get them on subscription on Amazon to save money and get the big pack.
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Reviewed in the United States on March 21, 2026
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Su
Fort Morgan, US
★★★★★ 5
Recommended
Size: Size 5, Unit Count: 100
I absolutely love these Pampers Cruisers 360 Size 5 diapers! As a parent of an active toddler, diaper changes used to be such a struggle—but these have made a huge difference. The pull-on style is a game changer. I can quickly put them on even when my child is moving around, and the 360° stretchy waistband fits snugly without being too tight. It really feels like little “training pants,” which is great as we slowly move toward potty training. What impressed me the most is how leak-proof and absorbent they are. Even during long days or naps, they keep my child dry and comfortable. The material is also very soft and gentle on the skin, and we haven’t had any irritation or rashes at all. (They’re actually designed to be gentle and hypoallergenic, which gives extra peace of mind.) I also love the easy tear-away sides and disposal tape—it makes cleanup so quick and mess-free. Overall, these diapers are perfect for active toddlers. Comfortable, reliable, and super convenient—I highly recommend them!
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Reviewed in the United States on April 28, 2026
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Altamirano
Lowell, US
★★★★★ 5
It's worth it.
Size: Size 7, Unit Count: 44, Size: Size 7, Unit Count: 44
I would like to provide feedback regarding a recent diaper experience. My toddler, who has a tendency to remove his diaper, has previously used Parent's Choice products since birth without issue. However, I have recently encountered a problem with both their standard diapers and Pull-Ups, specifically concerning the coverage in the gluteal region. This has led to the diaper riding up and causing a significant rash due to friction. I am pleased to report that after two hours of use, the current diaper has exceeded my expectations. My son has not removed it, and the coverage in the gluteal area is excellent. I will provide an update should any leakage occur. I also appreciate the baby powder scent and the overall quality of the product. While the price point is slightly higher than I typically prefer for diapers, my son is approaching three years old and will soon be transitioning to potty training.
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Reviewed in the United States on May 3, 2026
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Yela
West Palm Beach, US
★★★★★ 5
Movement freedom and quick changes: The ideal diaper for active babies
Size: Size 5, Unit Count: 56, Size: Size 5, Unit Count: 56
360° Flexible Fit: The standout feature is the 360° stretchy waistband that adapts perfectly to the baby's body, preventing gaps and allowing full, unrestricted movement. • Easy On and Off: Being a "Pull-On" style, it slides up in a second. For removal, it features the practical "e-z off" tabs on the sides that tear easily for a hygienic and fast change. • Designed for Active Babies: The packaging highlights an All-Around Fit specifically engineered for dynamic little ones who need protection that keeps up with them. If your baby has started moving and diaper changes have become a 'wrestling match' with traditional tabs, Pampers Cruisers 360° are the ultimate solution. They offer the peace of mind of Pampers protection with the convenience of pull-up underwear. A great investment for your child's exploration stage.
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Reviewed in the United States on May 1, 2026

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