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Description
Galectin-4 Protein, HumanProduct Specification Species Human Synonyms Antigen NY CO 27, GAL4, gal 4, galectin 4, Galectin4, L 36 lactose binding protein, L36LBP, Lactose binding lectin 4, lectin galactoside binding soluble 4, LGALS4 Accession P56470 Amino Acid Sequence Ala2 Ile323 Expression System E. coli Molecular Weight 36kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Physical Appearance Lyophilized Powder Storage Buffer 250mM Tris, 150mM NaCl,
Product Specification
| Species | Human |
| Synonyms | Antigen NY-CO-27, GAL4, gal-4, galectin 4, Galectin4, L-36 lactose-binding protein, L36LBP, Lactose-binding lectin 4, lectin galactoside-binding soluble 4, LGALS4 |
| Accession | P56470 |
| Amino Acid Sequence | Ala2-Ile323 |
| Expression System | E.coli |
| Molecular Weight | 36kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 250mM Tris, 150mM NaCl, 3mM DTT, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Poland P A. et al. (2022) Cloning, Expression, and Purification of Galectins for In Vitro Studies. Methods in Molecular Biology. 2442: 41-54. 2、Rustiguel J K. et al. (2016) Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4. 118: 39-48. 3、Stancic M. et al. (2012) Galectin-4, a Novel Neuronal Regulator of Myelination. GLIA. 60(6): 919-935. |
Background
Galectins are best known for their ability to bind glycoconjugates containing β-galactose, but classification of these small proteins within the galectin family is also defined by amino acid homology within structural domains and exon/intron junctions within genes. Galectin-4 (Gal4), a tandem-repeat type galectin, is expressed in healthy epithelium of the gastrointestinal tract. Altered levels of Gal4 expression are associated with different types of cancer, suggesting its usage as a diagnostic marker as well as target for drug development. The functional data available for this class of proteins suggest that the wide spectrum of cellular activities reported for Gal4 relies on distinct glycan specificity and structural characteristics of its two carbohydrate recognition domains. Gal4, a tandem-repeat-type lectin with affinity to sulfatide and non-sialylated termini of N-glycans, has the ability to regulate adhesion of cells to ECM components and is also involved in polarized membrane trafficking.
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4.3 ★★★★★
Based on 23 reviews
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Product Reviews
★★★★★ 5
Comfortable Shoes Right Out of the Box
Size: 9, Color: Black
I bought these shoes for my husband. He has a very hard time finding quality, comfortable shoes. These shoes are just as comfortable as his New Balance. He uses them as a dress shoe and wears them at least once a week. There was no break in period necessary. They were comfortable right out of the box! The only thing we didn't like was the white sole color. Once I knew he was going to keep them, I used a black sharpie marker to color the soles black. Instant amazing, comfortable dress shoes. They were well worth the cost. If you or your SO needs a comfortable pair of shoes, we highly recommend them.
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Reviewed in the United States on September 2, 2025
★★★★★ 1
Paid for new, received used.
Size: 9.5 Wide, Color: Cognac, Size: 9.5 Wide, Color: Cognac
Arrived dirty as if someone whore it for more than a few days. Maybe I was mistaken, but I saw nothing about “previously used” on the Amazon page. Returned it.
I would suggest that the company use quality control when it comes to shipping. The shoes seem find otherwise. I ordered 9.5 and it was just a bit tight. If I reorder I will go for size 10.
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Reviewed in the United States on June 11, 2026
★★★★★ 5
Overall Great.
Size: 10.5 Wide, Color: Black
Great product. Great value. Great style. Overall great.
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Reviewed in the United States on March 3, 2026
★★★★★ 3
Decent Shoes with Misleading Description (Not Leather)
Size: 12 Wide, Color: Black, Size: 12 Wide, Color: Black
I only look for leather when I’m purchasing dress shoes. Under the description “details” on this item it lists the shoe as leather upper and inner lining. A photo shows “genuine Napa leather lining”. If you keep reading (which I have now that I’ve received the shoes) it shows “faux leather” in the small print and that is not “leather”. I run a small leather business and this irks me because it’s clearly false advertising. The details also show the product is made in Brazil but when they arrived today, the shoe tag shows “Made in China” and “Man Made upper and lower”. I don’t hate the shoes. They look nice. What I know is they won’t hold up over time like leather, which is why the description should be accurate and not misleading.
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Reviewed in the United States on March 28, 2026
★★★★★ 5
Great piece of equipment. Worked for mouse, hard drive, and digital camera all into a laptop.
Works great. I used to plug in a mouse, an external hard drive, and an overhead Nikon digital camera for historic digitization of documents and books. It small and compatible and there were no connection or power problems. It feels well built and sturdy and the cord connection to the device is strong and flexible.
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Reviewed in the United States on May 2, 2026
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