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Description
Galectin-4 His Tag Protein, HumanProduct Specification Species Human Synonyms Galectin 4, LGALS4, L36LBP, Antigen NY CO 27, Lactose binding lectin 4 Accession P56470 1 Amino Acid Sequence Met 1 Ile323, with N 8*His Expression System HEK293 Molecular Weight 38 42kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4, 2mM DTT Reconstitution Reconstitute at 0. 1 1 mg ml according to the size
Product Specification
| Species | Human |
| Synonyms | Galectin-4, LGALS4, L36LBP, Antigen NY-CO-27, Lactose-binding lectin 4 |
| Accession | P56470-1 |
| Amino Acid Sequence | Met 1-Ile323, with N-8*His |
| Expression System | HEK293 |
| Molecular Weight | 38-42kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 2mM DTT |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Yang R Y. et al. 2008 Galectins: structure, function and therapeutic potential. Expert Rev Mol Med. 10: e17. 2、Ideo H. et al. 2007 Recognition mechanism of galectin-4 for cholesterol 3-sulfate. J Biol Chem. 282(29): 21081-21089. |
Background
Galectins are a family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins.Galectin-4, a tandem-repeat-type lectin with affinity to sulfatide and nonsialylated termini of N-glycans, has the ability to regulate adhesion of cells to ECM components and is also involved in polarized membrane trafficking.Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. Galectin-4 can also bind lung, spleen and kidney macrophages, although its expression is normally low in these tissues. Neurons and OLGs were identified as a possible source of galectin-4, both in vitro and in vivo. In culture, neurons but not OLGs released galectin-4. In co-cultures, a reduced release of endogenous galectin-4 correlated with the onset of myelination. Galectin-4-reactive sites are transiently expressed on processes of premyelinating primary OLGs, but not on neurons. Neuronal galactin-4 is a candidate for a soluble regulator of OLG differentiation and myelination.
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4.6 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 5
Helps with redness and softens skin
I have sensitive, mild rosacea skin. Had a facial recently and the aesthetician suggested I get a serum to help with moisturizer as I am almost 40. I’ve tried a lot of serums and either they are sticky and not really hydrating or break my skin out in a rash. This serum is amazing. Helps calm the redness in my cheeks and my skin is moisturized and soft all day. It feels a little sticky at first but it goes away. I apply in this order OSEA sea mineral mist toner to prep the skin, this serum and top off with Chanel La Solution 10 for sensitive skin.
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Reviewed in the United States on December 27, 2025
★★★★★ 5
Sensitive skin
Such a good product. I use after micro needling when skin is sensitive. Also a great product to use as a barrier serum when starting tretinoin cream.
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Reviewed in the United States on April 24, 2026
★★★★★ 5
Saved my skin during an eczema flare up
This saved my skin!
I had an eczema flare on my face, and my usual products weren’t working. A friend recommended the Avene brand and within 3 days of using this rescue barrier serum, my flare was almost completely gone! This saved my face!
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Reviewed in the United States on April 11, 2026
★★★★★ 1
PLEASE REVIEW — FORMULA CHANGED!!!
I wish I would’ve posted a review PRIOR to the formula changing but just know that I LOVED this serum. I’ve struggled with hormonal acne (PCOS) and eczema for as long as I can remember. Finally, last summer my dermatologist put me on (3) different RX including Spironolactone and Accutane. I was so tired so I stopped everything except for CeraVe cleanser, retinol (Tretinoin) and CeraVe healing ointment. My made up skin routine was working until I used too much Tretinoin and burned my face. I had read great reviews about this product so I thought, I might as well try it — and IT WORKED! I’ve been using this product for almost a year and I loved it. However, 3 weeks ago when I ordered it, I noticed the bottle had a green tint. I could tell after one use that the feel of the serum was different, more watery, not as thick as it used to be. The smell was also different. Still, I kept using it for nearly 2 weeks and I experienced 2 breakouts! Sure enough, I stopped the product and within a few days, my skin was back to normal. I am very upset because as someone who has extremely sensitive skin, this worked but unfortunately, the new formula isn’t for me.
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Gentle and Perfect for Sensitive Skin
Style: 16.7 fl oz
This is a great micellar water! I have very sensitive, acne-prone skin, and it hasn’t caused any redness or irritation at all. It removes makeup very easily and leaves my skin feeling clean and refreshed afterward. I also like to follow up with a mild face wash as part of a double cleanse routine; overall, it feels gentle, effective, and perfect for sensitive skin.
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Reviewed in the United States on May 21, 2026