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Description
PCNA Recombinant Rabbit mAb (SDT-297-116)Product Specification Host Rabbit Antigen PCNA Synonyms Proliferating cell nuclear antigen, Cyclin Immunogen Synthetic Peptide Location Nucleus Accession P12004 Clone Number SDT 297 116 Antibody Type Recombinant mAb Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu, Ms, Rt Predicted Reactivity Av, Bv, Hm Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0.
Product Specification
| Host | Rabbit |
| Antigen | PCNA |
| Synonyms | Proliferating cell nuclear antigen, Cyclin |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | P12004 |
| Clone Number | SDT-297-116 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Av, Bv, Hm |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC | 1:2000 | |
| ICC | 1:500 | |
| ICFCM | 1:50 |
Background
Proliferating cell nuclear antigen (PCNA) is a type of DNA clamp that acts as a DNA polymerase in eukaryotic cells δ. The processing factor of is crucial for replication. PCNA is a homologous trimer that achieves its processability by surrounding DNA, where it serves as a scaffold for recruiting proteins involved in DNA replication, DNA repair, chromatin remodeling, and epigenetics. It is expressed in most tumors as a proliferative antigen.
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