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Description
PE-Cy7 Mouse Anti-Human CD34 Antibody (S-2802)Product Specification Host Mouse Antigen CD34 Synonyms Hematopoietic progenitor cell antigen CD34 Location Membrane Accession P28906 Clone Number S 2802 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation PE Cy7 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution,
Product Specification
| Host | Mouse |
| Antigen | CD34 |
| Synonyms | Hematopoietic progenitor cell antigen CD34 |
| Location | Membrane |
| Accession | P28906 |
| Clone Number | S-2802 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | PE-Cy7 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD34 is a transmembrane phosphoglycoprotein primarily known as a biomarker for hematopoietic stem and progenitor cells, as well as endothelial cells. It functions as an adhesion molecule, mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 is crucial in clinical settings for the isolation and enrichment of hematopoietic stem cells used in bone marrow transplantation. Although it is predominantly associated with hematopoietic cells, CD34 is also expressed on various non-hematopoietic cells, including endothelial precursors, fibrocytes, and muscle satellite cells. Its exact function remains under investigation, but it is believed to play roles in cell proliferation, differentiation, and intracellular signaling.
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