SKU: 54337051129

Saffron Extract

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Description

Saffron ExtractImbalances in brain neurotransmitters such as serotonin, dopamine, and GABA contribute to symptoms of mood changes and anxiety.[1,2,3] Saffron Extract promotes serotonin and neurotransmitter balance in the brain, helping to reduce levels of anxiousness and stress response for a sense of calm.* Supplementing with Saffron Extract supports healthy mood balance and positive outlook and provides antioxidant support for healthy inflammatory response and

Imbalances in brain neurotransmitters such as serotonin, dopamine, and GABA contribute to symptoms of mood changes and anxiety.[1,2,3] Saffron Extract promotes serotonin and neurotransmitter balance in the brain, helping to reduce levels of anxiousness and stress response for a sense of calm.*

Supplementing with Saffron Extract supports healthy mood balance and positive outlook and provides antioxidant support for healthy inflammatory response and central (CNS) nervous system function. Adding this supplement to your daily regimen can support healthy brain function and healthy vitality in addition to helping support a healthy response to anxiousness for restful sleep. Saffron can even support a positive response to PMS symptoms.*

Vital Nutrients Saffron Extract comes in small, easy-to-take capsules using bioactive saffron components at clinically studied doses.[4,5]

It works by supporting the balance of serotonin metabolism in the microbiome, influencing tryptophan and serotonin responses in the brain, which also indirectly supports healthy dopamine and GABA expression, as well as modulation of the HPA axis, antioxidant support, and immune support.[4,6]

Packaging and label may vary.

References:
1. Pourhamzeh M. Cell Mol Neurobiol. 2022;42(6):1671-1692.
2. Grace A. Nat Rev Neurosci. 2016;17(8):524-532.
3. Conde KM. Metabolism. 2025;163:156099.
4. Lin S et al. Psychopharmacology. 2022;239:3657-3677.
5. Mena-Garcia A et al. Foods. 2023;12:1634.
6. Shafiee M. J Affect Disord. 2018;227:330-337.

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SKU: 54337051129

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4.0 ★★★★★
Based on 12 reviews
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M
Verified Purchase
Mindy Thegreatest
Natrona Heights, US
★★★★★ 5
Very durable! Great value!
Color: Green
My dog loves this toy, heavy duty, she has not chewed it up yet!
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Reviewed in the United States on March 14, 2026
S
Verified Purchase
Sharon r Hatch
Belleville, US
★★★★★ 5
Only “tough” toy my Doberman loves!
Pattern Name: Octopus
Not indestructible, but last a good long while. Definitely worth the money and lasts longer than any other plush toys we’ve had (which is all my dog will play with). It’s for sure my Dobermans favorite, I’ve ordered probably 10 at this point. He gets the stuffing out after a month or two and we open a new one. He’s picky with toys, either destroys them or ignores them, but he never gets bored with his octopus! 🐙 He sneaks one outside once in a while and the neighbor’s dogs steal it. They love it too and thankfully can’t destroy before I retrieve it.
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Reviewed in the United States on December 22, 2025
C
Verified Purchase
Christina
Waukegan, US
★★★★★ 5
Great for a Pitball
Pattern Name: Octopus
I have a Pitbull and she absolutely loves this toy. I always wait a while before giving a review. She has had this toy Since the beginning of July and she is still playing with this toy. It does have little holes but it is still going. She loves it. Playing tug of war with her. I also take it and wrap it around her collar and watch her dance around trying to get it out(I don't leave it there long). This a great buy. I also bought and extra one so when this one does finally dies she will have another. The material is strong, The sound is about normal for a squeaky toy.
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Reviewed in the United States on December 30, 2025
R
Verified Purchase
Robert
Phoenix, US
★★★★★ 3
Cute, but not tough enough.
Pattern Name: Octopus
This toy is cute, my pug loves it, and I like how the legs are strong but the top of the octopuses head isn't tough enough which is worrisome because thats where the squeaker is. It might work out for a smaller dog though.
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Reviewed in the United States on June 12, 2026
M
Verified Purchase
Millie
Grantham, US
★★★★★ 5
Fun Resilient Chew Toy
Pattern Name: Octopus
I have a boxer/pit mix and she loves this! I bought it 4 months ago and it’s still going strong so I know it’s quality made and perfect for dogs that like to chew and play tug of war. It has been chew resistant for my girl and she loves the little squeak. I just throw it in the washer when I wash her bed. Great value and a safe toy that’s a good size for a medium to large dog.
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Reviewed in the United States on May 4, 2026

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