SKU: 67851424408

CARDARINE (GW-501516) Poeder, 1gr

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Description

CARDARINE (GW-501516) Poeder, 1grCardarine GW 501516 Wat is GW 501516? GW 501516 is een PPAR agonist (Peroxisome Proliferator Activated Receptor), oorspronkelijk ontwikkeld door GlaxoSmithKline voor de behandeling van hyperlipidemie, obesitas, metabole disfunctie en hartziekten. De verbinding staat ook bekend als Endurobol of Cardarine, en wordt in onderzoek vaak aangeduid als een PPAR agonist. Onderzoek toont aan dat GW 501516 invloed heeft op vetzuurmetabolisme,

Cardarine GW-501516

Wat is GW-501516?

GW-501516 is een PPAR-agonist (Peroxisome Proliferator-Activated Receptor), oorspronkelijk ontwikkeld door GlaxoSmithKline voor de behandeling van hyperlipidemie, obesitas, metabole disfunctie en hartziekten. De verbinding staat ook bekend als Endurobol of Cardarine, en wordt in onderzoek vaak aangeduid als een PPARδ-agonist.

Onderzoek toont aan dat GW-501516 invloed heeft op vetzuurmetabolisme, skeletspieruithoudingsvermogen, en glucose-insulinebalans. PPARδ speelt daarnaast een rol in mitochondriale ademhaling, ontstekingsregulatie, spierherstel en keratinocytdifferentiatie (bron).

Onderzoek naar uithoudingsvermogen en vetverbranding

In een muizenstudie leidde drie weken toediening van GW-501516 tot een toename van 31,2% in loopsnelheid bij getrainde ratten en 68,6% bij ongetrainde. Na slechts één week werd al een verbetering van 48,6% waargenomen ten opzichte van de controlegroep. De combinatie van Cardarine en fysieke training leidde tot verhoogde vetzuuroxidatie en energiegebruik uit lange keten vetzuren (bron).

De activering van PPARδ beïnvloedde ook spierherprogrammering via genexpressie voor contractiele eiwitten, mitochondriale biogenese en vetverbranding.

Effecten op metabole markers en ontsteking

Bij muizen op een vetrijk dieet leidde GW-501516 tot verminderde insulineresistentie, verhoogde mitochondriale activiteit, lagere vetopslag in spieren en verlaagde glucose- en insulineniveaus (bron).

Een andere studie bij fructosegevoede ratten toonde afname van leverontstekingen en verlaging van lipogene genexpressie aan. Tegelijk werden genen die vetverbranding stimuleren verhoogd (bron).

Onderzoek bij resusapen liet verbeteringen zien in HDL, LDL, triglyceriden en insulineniveaus, wat Cardarine potentieel maakt als onderzoeksobject voor cardiovasculaire aandoeningen en metabool syndroom (bron).

🧪 Inhoud

In het potje zit 1 gram puur GW-501516 poeder.
Een maatschep is niet inbegrepen.
Voor nauwkeurige afweging raden we aan om een precisieweegschaal te gebruiken.

📄 Disclaimer

Dit materiaal wordt uitsluitend verkocht voor gebruik in laboratoriumonderzoek. Verkoopvoorwaarden zijn van toepassing. Niet voor menselijke consumptie, noch voor medisch, diergeneeskundig of huishoudelijk gebruik. Maak uzelf vertrouwd met onze DISCLAIMER voordat u bestelt.

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SKU: 67851424408

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4.2 ★★★★★
Based on 14 reviews
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Madi lohr
Battle Creek, US
★★★★★ 5
my new favorite book
Format: Kindle
Ok so I never write reviews but this book was so good I felt the need to write this. Firstly your introduced to Huntyr you see her closed off hard core badass than towards the end you see the most subtle change and growth it’s amazing and the enemies to friends to lovers was just perfect, AND THE TWIST AT THE END GOT ME GOOD! You see one spicy scene the whole book but it doesn’t even MATTER BECAUSE THE BOOK WAS THAT GOOD. I’ve read 85 books in 2023-2024 so far and I’m pround to say this is my all time favorite. I’m so excited to read more of Emily Blackwoods books, this was my first time reading one of hers and I’m glad I did because HOLY!! Well done Emily well done
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Reviewed in the United States on February 23, 2024
R
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Robin
Natrona Heights, US
★★★★★ 4
Fast paced romantasy you will not want to put down!
Format: Kindle
4.25 stars! I LOVED this book with similar vibes to Hush Hush, Fourth Wing, and The Serpent and the Wings of Night! It was fast paced with easy world building and will keep you turning the pages late into the night because you will not want to put it down! Huntyr is a fierce bad@ss FMC trained to kill vampyres her entire life. She is sent on a mission to go to the academy and earn her spot into The Golden City. Upon arrival, she is forced to room with the delicious fallen angel, Wolf, who is the only one who knows about her assassin identity. The romance, the plot twists, the secrets revealed, the battles, and the tantalizing training scenes had me hooked! And that ending…. I’m holding my breath in need to know hell! Read if you love: 🪽 Fae, Vampyres, Fallen Angels 🪽 Academy setting with magical trials 🪽 Forced proximity and slow burn 🪽 Rivals to lovers 🪽 Hidden identities and secrets 🪽 Tend your wounds “𝘖𝘧 𝘤𝘰𝘶𝘳𝘴𝘦 𝘐 𝘸𝘢𝘴 𝘸𝘢𝘵𝘤𝘩𝘪𝘯𝘨 𝘺𝘰𝘶. 𝘐 𝘤𝘰𝘶𝘭𝘥𝘯’𝘵 𝘭𝘰𝘰𝘬 𝘢𝘸𝘢𝘺 𝘧𝘰𝘳 𝘢 𝘮𝘰𝘮𝘦𝘯𝘵, 𝘦𝘷𝘦𝘯 𝘪𝘧 𝘐 𝘵𝘳𝘪𝘦𝘥.” “𝘐𝘧 𝘺𝘰𝘶 𝘸𝘢𝘯𝘵 𝘮𝘦 𝘰𝘯 𝘮𝘺 𝘬𝘯𝘦𝘦𝘴, 𝘏𝘶𝘯𝘵𝘳𝘦𝘴𝘴, 𝘢𝘭𝘭 𝘺𝘰𝘶 𝘩𝘢𝘷𝘦 𝘵𝘰 𝘥𝘰 𝘪𝘴 𝘢𝘴𝘬.” “𝘠𝘰𝘶 𝘥𝘰 𝘯𝘰𝘵 𝘬𝘯𝘰𝘸 𝘵𝘩𝘦 𝘷𝘪𝘰𝘭𝘦𝘯𝘤𝘦 𝘵𝘩𝘢𝘵 𝘳𝘶𝘯𝘴 𝘵𝘩𝘳𝘰𝘶𝘨𝘩 𝘮𝘺 𝘷𝘦𝘪𝘯𝘴, 𝘣𝘦𝘨𝘨𝘪𝘯𝘨 𝘮𝘦 𝘵𝘰 𝘰𝘣𝘭𝘪𝘵𝘦𝘳𝘢𝘵𝘦 𝘢𝘯𝘺𝘰𝘯𝘦 𝘸𝘩𝘰 𝘭𝘢𝘺𝘴 𝘢 𝘩𝘢𝘯𝘥 𝘰𝘯 𝘺𝘰𝘶.”
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 12, 2024
B
Verified Purchase
Bernadette Smith
Omaha, US
★★★★★ 5
Excellent Rivals to Lovers!!
Format: Kindle
The tension and banter between Huntyr and Wold was delectable. I absolutely love the fallen angel and all of his flaws. Huntyr is amazing too being a badass FMC with some major trauma. The world building was great and I enjoyed the training aspect of the story. The writing was immersive and was in the story the whole time. The ending had quite a twist that I hadn’t anticipated and made my jaw DROP. Excellent job! I also loved the narration. Laura is one of my fave narrators!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 15, 2025
E
Verified Purchase
❈ Elizabeth ❈ | Breakawayreads
Bozeman, US
★★★★★ 5
Fallen Angels, fae, vampires, oh my!
Format: Kindle
Rating: 4.5 | Spice: 2 (but a good slow-burn) • Main Characters: Huntyr and Wolf • I couldn’t wait to read this book; there was so much hype about it! And there was no doubt why. I fell in love with the characters and the plot itself. This book is mainly plot driven more than friction driven but it’s easy to follow along with. The characters are fun, easily understood. The main setting is at an academy where both the main characters are going through trials and building strength for the final test, The Transcendent. There are fantastic side characters as well. I loved the camaraderie between Huntyr and her friends. But we don’t like Lanson. 😆 We do have some plot twists that come into play throughout the book. Secrets and betrayal to be seen. I did adore Wolf and Huntyr’s relationship. It was a classic slow burn trope. They didn’t hit it off fast, but in time their feelings grew. I loved their banter, so sexy. Wolf is your next book boyfriend; Huntyr is your next vampire assassin independent bad-a*s female. Themes include loyalty, trust, self-discovery, a true slow burn romance. Side note: book ends on a angsty cliffhanger! • Emily, thank you for writing this awesome novel and I cannot wait to devour Book 2, Blood So Brutal! 😍 • Happy reading, my lovelies! xo
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Reviewed in the United States on January 21, 2024
M
Verified Purchase
MelsABookworm
Fort Morgan, US
★★★★★ 4
“My heart bows to you and you only, Huntress.”
Format: Kindle
3.5 🌟 This book popped up in my KU recommended reading suggestions and the synopsis sounded like what I was in the mood for. I'm so glad I took a chance on it. I went into this knowing absolutely nothing about it and ended up really liking it. I love when this happens. The main characters are likeable and I easily found myself rooting for them. There is a mystery element to each of their backstories that I enjoyed watching unfold and can't wait to get more of. Wolf, in particular, has me fixated. Love him. I found this to be an entertaining, addictive read with a plot that moves along at a good pace. It reads so easily I found myself very reluctant to put it down. Lots of twists and turns and the angst is there. A good set up for the next book to come, for sure. My issues with this book....the dialogue feels a bit juvenile at times and there is a repetitive over use of a particular word phrasing that I found myself giving the ole eye-roll to. There are, without a doubt, some pretty cliche moments that gave me a bit of the cringe. I think this could've certainly 100% benefited from more depth regarding the world building. Perhaps the world building was sacrificed to keep the pacing quick? Just a guess. Also, the lack of consistency of character for the FMC was really evident and so she feels quite illogical at times. Overall, this was a fun and enjoyable read that hit the spot well enough for me. That ending certainly has me impatiently pining for book 2!
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Reviewed in the United States on June 18, 2024

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