Circadian PM - 90 Capsules *

Circadian PM - 90 Capsules *Complete sleep management with neurotransmitter, cytokine, and histamine support* The importance of healthy sleep for overall health and well being cannot be overstated. Unfortunately, achieving quality sleep is a challenge for many people. Common biological contributors to poor sleep can include physical discomfort, stress, anxiety, high histamine levels, and low levels of sleep promoting neurotransmitters, such as gamma aminobutyric acid (GABA).[1]

Complete sleep management with neurotransmitter, cytokine, and histamine support*

The importance of healthy sleep for overall health and well-being cannot be overstated. Unfortunately, achieving quality sleep is a challenge for many people. Common biological contributors to poor sleep can include physical discomfort, stress, anxiety, high histamine levels, and low levels of sleep-promoting neurotransmitters, such as gamma-aminobutyric acid (GABA).[1]

A multifaceted approach is needed to support falling asleep faster, staying asleep longer, and achieving higher quality, more restful sleep. Circadian PM™ utilizes a blend of 10 ingredients, promoting multiple mechanisms of action to nurture healthy sleep.

Mechanisms of Action*

• Calms the central nervous system and promotes sleep initiation by:
  • Increasing GABA, the primary inhibitory central nervous system neurotransmitter*
  • Decreasing breakdown of GABA and its binding capacity *
  • Stimulating GABA receptors*
• Promotes undisrupted sleep by supporting healthy serotonin levels, leading to increased REM sleep*
• Reduces wakefulness by supporting healthy histamine levels in the brain*
• Supports a healthy response to anxiety, promoting better sleep*
• Promotes normal cytokine function to soothe physical discomfort and support neural cytokine levels*

Circadian PM™ features PharmaGABA®, the natural form of GABA, made through a natural fermentation process.  This results in a superior form of GABA  vs other synthetic options. Synthetic forms of GABA are less bio-available, as their molecular size is too large to pass the blood-brain barrier. PharmaGABA® is easily absorbed and binds to GABA receptors in the peripheral nervous system, activating the parasympathetic nervous system. This activation of the parasympathetic nervous system by PharmaGABA® is measurable within 5 to 30 minutes after ingestion .*

The unique blend of herbs, nutrients, and amino acids make Circadian PM™ a must-have formulation for patients dealing with sleep challenges and those who want to improve the quality of their sleep utilizing natural methods.

*This item may take longer to ship out*