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Description
Human CSF1R, His tagProduct Specification Species Human Synonyms CSF 1 receptor (CSF 1 R; CSF 1R; M CSF R), Proto oncogene c Fms, CD115, FMS Accession P07333 Amino Acid Sequence Protein sequence(P07333, Ile20 Asn320, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | CSF-1 receptor (CSF-1-R; CSF-1R; M-CSF-R), Proto-oncogene c-Fms, CD115, FMS |
| Accession | P07333 |
| Amino Acid Sequence | Protein sequence(P07333, Ile20-Asn320, with C-10*His) IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:34.6kDa Actual:50kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.
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4.1 ★★★★★
Based on 27 reviews
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Product Reviews
★★★★★ 5
Easy to install if you watch some online how to videos.
The water pump kit worked great on my 35 year old, 2 stroke, 100hp, Mercury Outboard.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 15, 2025
★★★★★ 4
Very good shipped and received fast
Missing one bottom gasket. Maybe factor made changes from old style
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Reviewed in the United States on July 10, 2021
★★★★★ 5
Good impeller kit
Great kit for impeller alpha one gen two outdrive. The only thing that was missing is the instructions as a reference.
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Reviewed in the United States on August 14, 2025
★★★★★ 5
Outboard impeller replacement kit.
This kit was for a 1999 Mercury Force 75 hp outboard motor. I purchased used and had not been run for a year. Impeller was hard and not flexible enough to pump water. The kit fixed that problem and the job took about 2 hours to complete. (I took my time). If you don't have a shop manual look for YouTube videos. I watched several and found one that matched the motor I was working on. Made things much simpler.
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Reviewed in the United States on April 28, 2022
★★★★★ 5
Excellent product
The water pump kit fits perfectly well on my 1997 Alpha 1 Gen+ Stern drive. Quality looks good and at reasonable price. I run the motorboat for 20 minutes and the water recirculation was constant
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 12, 2024
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