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Description
Human IgG1 Fc , His tagProduct Specification Species Human Synonyms Immunoglobulin heavy constant gamma 1, Ig gamma 1 chain C region, Ig gamma 1 chain C region EU, Ig gamma 1 chain C region KOL, Ig gamma 1 chain C region NIE, IGHG1 Accession P01857 Amino Acid Sequence Protein sequence(P01857, Asp104 Lys330(D239E,L241E), with C 10*His)
Product Specification
| Species | Human |
| Synonyms | Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1 |
| Accession | P01857 |
| Amino Acid Sequence | Protein sequence(P01857, Asp104-Lys330(D239E,L241E), with C-10*His) DKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEETKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.2kDa Actual:30kDa |
| Purity | ＞90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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4.8 ★★★★★
Based on 21 reviews
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Product Reviews
★★★★★ 5
Epic tales that still resonate
Format: Paperback
I dove into Dawson’s twin translation of The Iliad and The Odyssey hoping for clarity—and instead found myself struck by their emotional pull. Achilles’ fury, Hector’s honor, Odysseus’ longing for home—it all felt immediate and real. Dawson’s language flows so naturally, I forgot I was reading an ancient text. There were moments I stopped and sighed, moved by how these characters still speak to our hearts today.
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Reviewed in the United States on July 9, 2025
★★★★★ 5
A good weekend read
Format: Paperback, Format: Paperback
I’ve been taking my time with this, and it’s been surprisingly relaxing to read on slow mornings. It feels clear and easy to follow, which makes these stories feel alive instead of like homework. Glad I gave it a try.
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Reviewed in the United States on July 17, 2025
★★★★★ 5
Timeless adventure, beautifully retold
Format: Paperback
I started with The Iliad, expecting a dry history lesson, and ended up caught in the drama of gods and men. Then The Odyssey stole my evenings—each chapter like an invitation back into wonder. Superb translation.
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Reviewed in the United States on July 3, 2025
★★★★★ 5
Feels like sitting around a fire
Format: Paperback
I didn’t think I’d ever get through these stories, but this translation made it feel like someone was telling them to me, not lecturing. The battles in The Iliad felt sharp and real, and the long journey in The Odyssey pulled me in without getting lost in heavy words. I finished both feeling like I finally understood why these stories mattered, and they left me thinking about courage, anger, and coming home in a new way.
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Reviewed in the United States on July 17, 2025
★★★★★ 5
As a fan of epic I approve
Format: Paperback
So far, it’s really good. It’s intriguing and it’s holding my intention span pretty well. I would definitely recommend it and it’s very detailed, but not boring
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Reviewed in the United States on August 18, 2025