SKU: 4975583425

SOX10 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (SDT-R233)

$72.00 $80.00
Save 10%
No.2 Bestseller on nasasuma.com >

Pay in installments of $20.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 28 - Aug 2

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

SOX10 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (SDT-R233)Product Specification Host Rabbit Antigen SOX10 Synonyms Transcription factor SOX 10 Location Cytoplasm, Nucleus Accession P56693 Clone Number SDT R233 Antibody Type Recombinant mAb Isotype IgG Application ICC, IF, ICFCM Reactivity Hu, Ms, Rt Positive Sample A375 Purification Protein A Concentration 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of

Product Specification


Host Rabbit
Antigen SOX10
Synonyms Transcription factor SOX-10
Location Cytoplasm, Nucleus
Accession P56693
Clone Number SDT-R233
Antibody Type Recombinant mAb
Isotype IgG
Application ICC, IF, ICFCM
Reactivity Hu, Ms, Rt
Positive Sample A375
Purification Protein A
Concentration 2 mg/ml
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
ICC 1:200 Hu
IF 1:200 Hu, Ms, Rt
ICFCM 1:2000 Hu

Background

SOX10 (SRY-box transcription factor 10) is a 55-kDa member of the SOX family of high-mobility-group (HMG) DNA-binding transcription factors that acts as a master regulator of neural crest development, melanocyte specification, and oligodendrocyte differentiation by forming homodimers or heterodimers with other SOX proteins and binding to the consensus sequence A/TA/TCAAA/TG, thereby activating or repressing target genes such as MITF, MBP, and PLP1; mutations or chromosomal rearrangements affecting the SOX10 locus on 22q13.1 are linked to the neurocristopathy syndromes Waardenburg–Hirschsprung disease type 4 (WS4), PCWH (peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome, and Hirschsprung disease), and a subset of melanoma tumors where SOX10 serves as a sensitive and specific immunohistochemical marker, while its expression is also essential for the maintenance of Schwann cell and melanocyte lineages throughout adulthood.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 4975583425

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.3 ★★★★★
Based on 6 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
B
Verified Purchase
4bonbon
Dallas, US
★★★★★ 1
Tip will not stay saturated with color
Color: Honey Brown, Size: 1 Count (Pack of 1)
This is a pen with a nice felt tip. First time I used it, it glided on nicely. Second time used about it a week later, tip was dry and no matter how I tried, it would not saturate and provided no color. I even tried storing it with the tip facing down to make the color flood to the tip, but even after several days of standing it up that way, tip was still dry. What a waste of money. I just ordered their Easy Brow and Fill Tool, which is a stick of color that winds in and out and so far like it very much. Would recommend that and not this ink pen.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 30, 2022
L
Verified Purchase
Lisa Gagliardi
Whiting, US
★★★★★ 5
Always Perfect!
Color: Rich Brown, Size: 1 Count (Pack of 1)
The best brow liner I have ever used. My eyebrows have thinned over the years because of a thyroid condition and I have been drawing them on since I had was in my thirties. I believe it really retains my youth and the fact that this is a liquid helps me keep the hairs in place that I already have up there. I do not go anywhere without my eyebrow liner. Add this to your makeup kit! You will thank me.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 1, 2026
T
Verified Purchase
Tracy
Fort Morgan, US
★★★★★ 5
Easy To Use
Color: Soft Brown, Size: 1 Count (Pack of 1)
Easy to use. Looks natural. Great product. I definitely recommend it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 28, 2025
K
Verified Purchase
Kathryn Roberts
Fort Morgan, US
★★★★★ 5
Great Brow Pen
Color: Dark Brown, Color: Dark Brown
I love this brow pen; it’s my favorite brow product I’ve ever used. If you aren’t already here because of Katie Jane Hughes on Instagram, I recommend searching her (@katiejanehughes) and she has an instastory highlight about how she uses this pen. I find it’s extremely important to store these pens upside down to allow the “ink” to travel down to the brush, and also to keep the brush pointed down as you use feathering strokes to paint the shape and hairs you want. The faster you work, the better; some people say the pen dries out, though I find I have plenty of time for both brows, especially if I’m using more than one color. You don’t need to use a primer in advance of using these pens (some peoples he trouble if they DO use primer; something about the slippiness makes it difficult for the pen to stick. I’ve never had that issue myself but if you’re struggling try without primer). I also tend to use a brow gel on top of this, but only to wrangle my brow hairs into one direction. You certainly don’t need to. I’ve attached some swatches, since I had a really hard time finding any online. The main difference between “soft black” and “dark brown” is that the dark brown has a warm undertone and is much more opaque than soft black in my opinion. The idea is to use short, light strokes to apply this, so nothing will be too strong unless you want it to be. I tend to go in with soft black first to get the shape I want at the arch and to do some filling in, then I use medium brown on the inside of my brows and also to fill in, and then I use dark brown last just where I need some extra coverage. I certainly don’t recommend being this extra; I bought the colors to see what they looked like and found that I like the dimension of using multiples and also that it helps ensure my pens don’t dry out at an inopportune time.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 16, 2019
R
Verified Purchase
Ren
Carnegie, US
★★★★★ 5
my Holy Grail Brow product thank you Katie Jane Hughes
Color: Medium Brown
This is my 3rd or 4th? re-order. I don't know what I will do if it gets discontinued for any reason:( I have very sparse , light brows. This is the only thing in the world that has ever let me make realistic brow hairs, with a small learning curve that don't look drawn on, or fade during the day. The pen will dry out if not left stored upside down. It lasts me at least a few months. I'm always ordering another one before it runs out just so that I'll have a back up. Thank you allure! Glossier has a version of this, but it's less product for more money and the tip isn't a thin as this one. I have even ordered this for friends, it's that good.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 6, 2020

recommand products

Human CAMP ELISA Kit
184.12
Mouse AIF1 ELISA Kit
255.56
Human PARK2 ELISA Kit
184.12
Human CAM ELISA Kit
184.12
Human Resistin ELISA Kit
184.12