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Description
S-RMab® MSH6 Recombinant Rabbit mAb,PBS Only (SDT-R094)Product Specification Host Rabbit Antigen MSH6 Synonyms hMSH6,GTBP Immunogen N A Location Nucleus Accession P52701 Clone Number SDT R094 Antibody Type Rabbit mAb Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt, 4C as supplied Dilution application dilution species WB 1: 1000 Hu, Ms IHC P 1: 500 Hu, Ms, Rt ICC 1:
Product Specification
| Host | Rabbit |
| Antigen | MSH6 |
| Synonyms | hMSH6,GTBP |
| Immunogen | N/A |
| Location | Nucleus |
| Accession | P52701 |
| Clone Number | SDT-R094 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt, 4°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
| IHC-P | 1:500 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
Background
DNA mismatch repair protein (MSH6) is one of the mismatch repair proteins and is encoded by the MSH6 gene, which is located on chromosome 2 and is 23,806 bp in length, including 10 exons and 83 untranslated regions. The MSH6 protein consists of 1,358 amino acid residues and forms a heterodimer with another mismatch repair protein, MSH2. The MSH2-MSH6 heterodimeric complex is able to recognize base-base substitution and single-base insertion/deletion mismatches. Germline mutations of MSH6 lead to high susceptibility to glioma, as well as a number of benign or malignant tumors in other organs.
Shipping Notes
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Exchange/Return Notes
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