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Description
Human IL-22 OneStep ELISA KitProduct Specification Antigen IL 22 Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Hu Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Kit Precision Intra assay: 4. 7% Inter assay: 5. 9% Sample type Cell culture supernatant, Serum,Plasma Assay type Sandwich (quantitative) Sensitivity 1. 002 pg ml Range 3. 125 pg mL 200 pg mL Recovery Cell culture supernatant: 99%
Product Specification
| Antigen | IL-22 |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Hu |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Kit
| Precision | Intra-assay:4.7%； Inter-assay: 5.9% |
| Sample type | Cell culture supernatant, Serum,Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 1.002 pg/ml |
| Range | 3.125 pg/mL – 200 pg/mL |
| Recovery | Cell culture supernatant: 99% Serum: 95% Plasma: 102% |
| Assay time | 60 minutes |
| Species reactivity | Human |
Background
Interleukin-22(IL-22) is a member of the IL10 family of cytokines that mediate cellular inflammatory responses and functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. IL-22 has a role in the remodeling of the uterine tissue in the inflammatory environment by regulating epithelial-mesenchymal transition markers called E- and N-cadherin. Therefore, IL-22 contributes to the proper regeneration of endometrial layers after inflammation-triggered abortion. Thus, it might have a practical significance to be utilized as a treatment option postpartum (enhanced regeneration function) and in secondary infertility caused by inflammation (enhanced barrier/protector function). IL-22 is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2).
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