SKU: 98237798441

CD3 epsilon&CD3 delta Heterodimer Fc, His Tag&Fc, Flag Tag Protein, Human

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Description

CD3 epsilon&CD3 delta Heterodimer Fc, His Tag&Fc, Flag Tag Protein, HumanProduct Specification Species Human Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D Accession P07766 1(CD3E)P04234 1(CD3D) Amino Acid Sequence Asp 23 Asp 126 (CD3E) with hIgG1 Fc Tag at the C Terminus, followed by His Tag Phe 22 Ala 105 (CD3D) with hIgG1 Fc Tag at the C Terminus, followed by Flag Tag Expression System HEK293 Molecular Weight 40 55kDa (Reducing) Purity 95% by SDS PAGE & HPLC Conjugation Unconjugated Tag His Tag, Flag Tag, Human IgG1 Fc

Product Specification


Species Human
Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D
Accession P07766-1(CD3E)、P04234-1(CD3D)
Amino Acid Sequence

Asp 23 - Asp 126 (CD3E) with hIgG1 Fc Tag at the C-Terminus, followed by His Tag
Phe 22 - Ala 105 (CD3D) with hIgG1 Fc Tag at the C-Terminus, followed by Flag Tag
Expression System HEK293
Molecular Weight

40-55kDa (Reducing)

Purity ＞95% by SDS-PAGE & HPLC
Conjugation Unconjugated
Tag His Tag, Flag Tag, Human IgG1 Fc
Physical Appearance Lyophilized powder
Storage Buffer

PBS, PH7.4, 5% trehalose
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function. Sci Rep. 2025 Feb 25;15(1):6769.
2. A rationally designed fully human EGFRvIII:CD3-targeted bispecific antibody redirects human T cells to treat patient-derived intracerebral malignant glioma.[J]. Clinical Cancer Research, 2018:clincanres.0126.2017.

Background

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 98237798441

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4.6 ★★★★★
Based on 11 reviews
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L
Verified Purchase
louctiel
Houston, US
★★★★★ 4
A Frother that Won't Turn Off? Great Service. Lost Package. Great Hot Chocolate. Worth It!
Color: Black, Size: Z1 Motor + Batteries
I saw this item (or one similar) on an Alton Brown short video. He recommended a frother and I thought "what the heck? If AB recommends a uni-tasker, it must be something good." The item came in, loaded with batteries and all. I removed the plastic tab that interrupts the power and the unit kicked on. I wasn't pressing anything. It just started and would not stop. To return the item is not worth the time or money, especially since none of the "free return" options are anywhere close to me. Called the company and told them what had happened. I spoke with a very nice woman and after I described what happened, her response was not faux sympathy, but "that shouldn't have happened. We'll make it right." She offered not only to replace the unit, but send a second one free of charge. When I declined the second one, she said "take it for your troubles. Give it to a friend if you want." The order was sent out. Tracking via USPS was sent. The package was supposed to be delivered on a Friday, which was great as we were supposed to get cold temps and snow. I was anticipating making frothy hot chocolate. Suddenly the tracking showed the package being delivered. It was not. You cannot ask the USPS to find a package for 7 days and my local post office doesn't answer the phone. Disappointed, I started to make dinner and looked out the window and I could see my postal carrier's truck a block away. I waddled over to the truck and talked to her. She said "I know where it is." She had delivered it 3 blocks away. Same house number, but different street. She went and found the package, brought it to me and Bob's your uncle. That night I made hot chocolate and used the frother. I was surprised that the long shaft did not vibrate or waiver. It stays true. The speed is fast, but not overly so. The thing made a difference. It seemed to make the hot chocolate "lighter" and smoother. I threw a piece of chocolate in the mug, waited a little and then frothed again using the frother. No issues with the frother. I now had frothy, really chocolate-ly hot chocolate. For kicks and on the advice of a friend, I added a tablespoon of peppermint schnapps and used the frother again. Best hot chocolate from a mix I ever had. The frother worked better than advertised. Woo Hoo!! Because the first one didn't work, I have to knock a star off of the rating for the product. But the customer service and actual accountability of the women with whom I spoke is refreshing in the world of product support and customer service. The item is really good and would recommend whole heartedly.
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Reviewed in the United States on January 11, 2026
A
Verified Purchase
Amazon Customer
Belleville, US
★★★★★ 5
Worth it!
Color: Absolute Black, Size: Z1 Motor + Batteries
It works great! Makes a big difference and my coffee is better! Easy to use and clean. The stand is perfect to keep it accessible. Only thing I would warn customers is to pay attention to instructions on how to insert batteries.
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Reviewed in the United States on May 18, 2026
M
Verified Purchase
Matthew Vincent
Alexandria, US
★★★★★ 5
High Quality and Surprisingly Powerful
Color: Absolute Black, Size: Z1 Motor + Batteries
The Pros: Unexpected Power: I usually know exactly what to expect with the products I order, but this unit really blew me away. It is surprisingly powerful and handles everything much better than I anticipated. Premium Batteries Included: It was a great surprise to find that it came with Duracell batteries. Seeing a name-brand battery included really speaks to the overall quality of the product and shows they aren't cutting corners. Solid Build: From the moment I set it up, the unit felt sturdy and well-constructed. It is rare to be this genuinely pleased with a purchase right out of the box. The Cons: Operating Noise: Because the motor is so powerful, it does produce a bit more noise than some weaker units. It isn't a dealbreaker, but it is noticeable during extended use. Bottom Line: This is a high-quality product that exceeded my expectations in both performance and presentation. The fact that it comes ready to go with reliable batteries is a huge plus. I am very pleased with this purchase.
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Reviewed in the United States on May 12, 2026
S
Verified Purchase
SR
Alexandria, US
★★★★★ 5
Pleasantly surprised.
Color: Absolute Black, Size: Z1 Motor + Batteries
Honestly, I bought this because it was on sale and I needed to add something to my cart to get one day free shipping. I had zero expectations and thought I'd use it when I travel and won't have access to my espresso machine but I'm blown away by what it can accomplish in its small form factor. It took 30s to froth the milk and it was well-incorporated into the milk, not with just foam on top and milk at the bottom. I could have the frothed milk all day. It's easier to clean than the steam wand and it does plant-based milk cold foam!! It blows the Ikea one out of the water for about the same price point. Glad I stumbled into it!
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Reviewed in the United States on May 26, 2026
J
Verified Purchase
Jami J. Woodyard
Battle Creek, US
★★★★★ 4
Works great for daily use, just be prepared to replace batteries
Color: Absolute Black, Size: Z1 Motor + Batteries
I use this every morning to mix protein powder into my coffee, and it works well. It is quick, easy to use, and does a great job blending everything smoothly without clumps. For the price, it’s a great little tool and has definitely been worth it for daily use. The only downside is that I do have to replace the batteries fairly often, about every 3–4 weeks with regular use. Overall, it’s a very convenient and effective frother, especially for the cost. I would recommend it, just keep extra batteries on hand if you plan to use it daily.
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Reviewed in the United States on June 9, 2026

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