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Description
Mouse IL-5(Culture Medium) OneStep ELISA KitProduct Specification Antigen IL 5 Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Ms Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 5. 1% Inter assay: 6. 1% Sample type Cell culture supernatant Assay type Sandwich (quantitative) Sensitivity 0. 788 pg mL Range 1. 95 pg mL 125 pg mL Recovery Cell culture supernatant: 90% Assay time 60
Product Specification
| Antigen | IL-5 |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Ms |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 5.1%； Inter-assay: 6.1% |
| Sample type | Cell culture supernatant |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 0.788 pg/mL |
| Range | 1.95 pg/mL – 125 pg/mL |
| Recovery | Cell culture supernatant: 90% |
| Assay time | 60 minutes |
| Species reactivity | Ms |
Background
Mouse Interleukin-5 (IL-5) is a Th2-derived cytokine critical for eosinophil biology. Produced primarily by activated T helper 2 cells and group 2 innate lymphoid cells (ILC2s) in mice, it signals through a heterodimeric receptor (IL-5Rα/βc) to regulate eosinophil differentiation, survival, and activation. This 45-kDa homodimeric glycoprotein drives allergic inflammation and anti-helminth immunity by promoting eosinophil migration to tissues and stimulating immunoglobulin production in B-1 cells. Its pivotal role in eosinophil-mediated pathologies makes it a key therapeutic target in murine asthma models and parasitic infections.
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